SKU: 51744310902

YK-11 Poeder, 1gr

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Description

YK-11 Poeder, 1grYK 11 Wat is YK 11? YK 11, ook bekend als myostine, is een selectieve androgeenreceptormodulator (SARM) die klinisch is aangetoond de androgeenreceptor gedeeltelijk te activeren en tegelijkertijd te functioneren als een myostatineremmer. Onderzoek en eigenschappen Een studie van Lee et al. onderzocht YK 11 als een potentieel middel voor spieropbouw en spierbehoud in situaties van sepsis. In het onderzoek kregen muizen tien dagen lang twee

YK-11

Wat is YK-11?

YK-11, ook bekend als myostine, is een selectieve androgeenreceptormodulator (SARM) die klinisch is aangetoond de androgeenreceptor gedeeltelijk te activeren en tegelijkertijd te functioneren als een myostatineremmer.

Onderzoek en eigenschappen

Een studie van Lee et al. onderzocht YK-11 als een potentieel middel voor spieropbouw en spierbehoud in situaties van sepsis. In het onderzoek kregen muizen tien dagen lang twee verschillende doses YK-11 toegediend (oraal, 350 mg/kg en 700 mg/kg), waarna ze blootgesteld werden aan een peritoneale injectie van E. coli-bacteriën.

Het onderzoek toonde aan dat YK-11 de werking van myostatine remt — een hormoon dat spiergroei beperkt (bron). Behandelde muizen behielden hun lichaamsmassa tijdens ziekte en hadden een gunstigere vet-spierverhouding ten opzichte van de controlegroep.

Na blootstelling aan systemische E. coli konden de behandelde muizen spiermassa in rug en dijen beter herstellen. Hun spiercellen waren bovendien beter bestand tegen atrofie.

Effecten op immuunrespons en organen

Naast effecten op spiermassa, had YK-11 ook impact op de immuunreactie. Behandeling resulteerde in een verlaging van endotoxines en ontstekingsmarkers in de longen. Ook biomarkers voor orgaanschade — zoals AST, ALT en BUN — waren verlaagd.

De eliminatie van schadelijke bacteriën uit organen werd verbeterd bij muizen die met YK-11 waren behandeld (bron), en het overlevingspercentage na sepsis bleek hoger tot aan het 72-uurmerk.

🧪 Inhoud

Het potje bevat 1 gram puur YK-11 poeder.
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📄 Disclaimer

Dit materiaal wordt uitsluitend verkocht voor gebruik in laboratoriumonderzoek. Verkoopvoorwaarden zijn van toepassing. Niet voor menselijke consumptie, noch voor medisch, diergeneeskundig of huishoudelijk gebruik. Maak uzelf vertrouwd met onze DISCLAIMER voordat u bestelt.

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SKU: 51744310902

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4.6 ★★★★★
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Lady B
Omaha, US
★★★★★ 5
Best affordable squeaker toy
Color: Crinkle Chicken (Brown), Size: Large, Color: Crinkle Chicken (Brown), Size: Large
my dog is obsessed with this toy, this has became his new comfort toy and after having this for about four months the legs are falling off but it’s very durable. The squeaker also moved from the head of the chicken to the body of the chicken but that’s after it was played with every single day. I love that it has two squeakers and it’s the perfect toy for my dog.
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Reviewed in the United States on May 6, 2026
A
Verified Purchase
Amazon Customer
Massapequa, US
★★★★★ 5
My dogs favorite toy EVER
Color: Crinkle Chicken (Brown), Size: Large
I have a Belgian Malinois who loves any and every toy, but this one is definitely her favorite. She will walk around the house constantly carrying it in her mouth, which is honestly adorable to watch. The squeakers only lasted a couple of months, but I don’t really consider that a downside—I’m kind of grateful they didn’t last forever given how much she plays with it. It still remains one of her most-loved toys even without them. My only word of caution is that if you work from home, this toy makes a lot of crinkling noise. And I mean A LOT. It’s great for keeping the dog entertained, but it can definitely get a little frustrating for humans trying to focus or take calls. Overall, it’s been a big hit in our house and easily one of her favorite toys.
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Reviewed in the United States on June 8, 2026
A
Verified Purchase
Amazon Customer
Boise, US
★★★★★ 5
Super cute
Color: Bunny (Mauve), Size: Small
Super cute and fuzzy. Definitely perfect size for a puppy and not too loud. The fur is very soft and the nose is sown on not a hard piece that can be chewed on. Very good quality too.
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Reviewed in the United States on June 3, 2026
B
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Buyer
Pawtucket, US
★★★★★ 4
Normally amazing
Color: Spiky Ball (Blue, Orange), Size: Medium
We have purchased these slightly spiky dog balls several times for our very strong jaw heavy chewer dogs and they’ve been amazing. They don’t break down they don’t get torn apart the squeakers don’t even pop out of them. So we ordered another package because we’ve lost a few outside to the lawnmower… oops and the package that got delivered today had only one ball that squeaks and the other does not. THIS IS A PROBLEM ! Unfortunately my female dog got to the new squeaking ball first and my male got to the non-squeaking ball and he was NOT happy. Basically once they claim a ball it’s theirs and the other dogs don’t go near the ball they claimed. So he’s following my female around and every time she squeaks the ball and I’m just waiting for him to attempt to take it from her causing damage to her. Normally… These are amazingly fun, tough, durable but also squeaking balls (that’s rare in a tough ball) that my dogs absolutely love. This time just got a bad batch I guess. When they squeak the dogs LOVE them. After several months of play the squeaker might break inside of the ball but the ball never comes apart or gets damaged. And we as the owners love that they don’t break down are not able to be ripped or torn even by our very strong jawed and big jaw muscle dogs. They are also great for in the house play because they’re small enough that they fit completely inside our dog‘s mouth but obviously not small enough to get swallowed so when we throw them in the house for fetch the dogs can jump up and catch them fully in their mouth so they don’t cause any damage to the walls when they hit the walls. They’re not super heavy but they’re incredibly durable. Definitely worth the price especially if you have heavy chewers or big jaw muscle dogs.
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Reviewed in the United States on April 28, 2026
M
Verified Purchase
MADDY
Omaha, US
★★★★★ 5
Best fun indestructible toy
Color: Crinkle Duck (Yellow), Size: Large
Truly indestructible no matter how much our oittie tries. She has owned it for three months works at destroying every day with no success. She carries it everywhere. Best purchase for chewer, more fun than the popular rubber heavy duty toy. Do not hesitate your pup will thank you for this fun distraction.
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Reviewed in the United States on May 30, 2026

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