SKU: 53871864278

Biotinylated IgG1 Fc&Avi&His Tag Protein, Human

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Description

Biotinylated IgG1 Fc&Avi&His Tag Protein, HumanProduct Specification Species Human Synonyms IgG1 Fc, Ig gamma 1 chain C region, IGHG1 Accession P01857 1 Amino Acid Sequence Pro100 Lys330, with C Avi tag and 6*His and IgG1 Fc Expression System HEK293 Molecular Weight 33kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Biotin Tag Avi Tag, His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4. Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in

Product Specification


Species Human
Synonyms IgG1 Fc, Ig gamma-1 chain C region, IGHG1
Accession P01857-1
Amino Acid Sequence Pro100-Lys330, with C-Avi tag and 6*His and IgG1 Fc
Expression System HEK293
Molecular Weight 33kDa (Reducing)
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Biotin
Tag Avi Tag, His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4.
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1. Peter Sondermann, Robert Huber, Vaughan Oosthuizen & Uwe Jacob: The 3.2-Å crystal structure of the human IgG1 Fc fragment–FcγRIII complex. Nature volume 406, pages267–273 (2000).

Background

Immunoglobulin G (IgG) is a monomer immunoglobulin, mainly involved in Immunoglobulin G (IgG) is a monomer immunoglobulin, mainly involved in secondary antibody reaction, plasma B cell synthesis and secretion, constitute 75% of human serum immunoglobulin. There are four subtypes of human IgG antibodies: IgG1, IgG2, IgG3, IgG4; mice IgG can be divided into five subtypes; IgG1, IgG2A, IgG2B, IgG2C and IgG3; rats have four subtypes: IgG1, IgG2A, IgG2B and IgG2C. The nomenclature of IgG subtypes of different species is independent, so there is no correlation among different genera. The content of IgG1 in serum accounts for about 60%, and the half-life in serum is about 21 days. After pepsin cleavage, IgG1 is divided into two antigenic binding sites F (ab) s and a highly conserved Fc fragment, and Fc has a highly conserved N-glycosylation site. IgG1 is the most potential subtype in tumor immunotherapy. The active form of IgG1 is bivalent monomer, and human IgG1 can also bind to mouse Fc γ receptor, so the obvious effect can be observed in mouse model.

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Exchange/Return Notes
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SKU: 53871864278

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Amazon Customer
Whiting, US
★★★★★ 5
Hydrating
A nice lotion, smell is good, not great, but hydrates well.
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Reviewed in the United States on May 23, 2026
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Karen Casey
Whiting, US
★★★★★ 5
Great quality
Loved this lotion. The smell was great, my skin was very moistuarized and soft after using it, it was a good thick, quality lotion that covered well.
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Reviewed in the United States on November 24, 2025
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Bobby Novosad
Natrona Heights, US
★★★★★ 5
This is the one to buy🔥
The reviews are all legit. No streaking, no staining, just a smooth, gradua,l natural looking glow🔥.
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Reviewed in the United States on May 23, 2026
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Colleen Stephens
Belleville, US
★★★★★ 5
Good product
Not too greasy and smells great
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Reviewed in the United States on June 1, 2026
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Zaya
Boise, US
★★★★★ 5
Perfect smell
Love Hawaiin products, they give me instant tropical vibes. Quick absorbing and instant skin softness
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Reviewed in the United States on December 20, 2025

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